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> home > Products > Primary Antibodies > Antibody Collections > Endometrium negative > Anti-LPHN2 Antibody
Anti-LPHN2 Antibody
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Application 
| WB, IHC |
|---|---|
| Primary Accession | O95490 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 163349 Da |
| Gene ID | 23266 |
|---|---|
| Other Names | KIAA0786; LEC1; LPHH1; Latrophilin-2; Calcium-independent alpha-latrotoxin receptor 2; CIRL-2; Latrophilin homolog 1; Lectomedin-1 |
| Target/Specificity | Recognizes endogenous levels of LPHN2 protein. |
| Dilution | WB~~1/500 - 1/1000 IHC~~1:100~500 |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | ADGRL2 (HGNC:18582) |
|---|---|
| Function | Orphan adhesion G-protein coupled receptor (aGPCR), which mediates synapse specificity (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of downstream effectors (By similarity). Following G-protein coupled receptor activation, associates with cell adhesion molecules that are expressed at the surface of adjacent cells to direct synapse specificity. Specifically mediates the establishment of perforant-path synapses on CA1-region pyramidal neurons in the hippocampus. Localizes to postsynaptic spines in excitatory synapses in the S.lacunosum- moleculare and interacts with presynaptic cell adhesion molecules, such as teneurins, promoting synapse formation (By similarity). |
| Cellular Location | Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q8JZZ7}; Multi-pass membrane protein |
| Tissue Location | Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to LPHN2
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$ 385.00
Cat# AP53822
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